Managing refrigerant and refrigeration systems can be a challenge for facilities and facility managers due in part to expanding regulatory requirements.  Section 608 (Refrigerant Management Requirements) of the Clean Air Act was updated to expand requirements for managing ozone-depleting substance (ODS) refrigerants to now also include ODS substitutes.  ODS substitutes which are now regulated include hydrofluorocarbons (HFCs) (e.g., R-410A, R-407C and R-134a), perfluorocarbons (PFCs) (e.g., R-116), and hydrofluoro-olefins (HFOs) (e.g., 1234YF).  These are collectively referred to as “non-exempt ODS substitutes.”